Formulation and evaluation of floating drug delivery system of famotidine

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Formulation and Evaluation of Floating Drug Delivery System of Famotidine

A multiple unit oral floating drug delivery system of famotidine was developed to prolong gastric residence time, target stomach mucosa and increase drug bioavailability. Drug and polymer compatibility was studied by subjecting physical mixtures of drug and polymers to differential scanning calorimetry. Cod liver oil entrapped calcium alginate beads containing famotidine, capable of floating in...

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Famotidine has been the most widely used drug for the treatment of peptic ulcer for many decades. The present investigation concerns the development and evaluation of floating tablets of famotidine which, after oral administration, are designed to prolong the gastric residence time, increase drug bioavailability and target the gastric ulcer. A floating drug delivery system (FDDS) was developed ...

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2010

ISSN: 0250-474X

DOI: 10.4103/0250-474x.84583